Appetite–regulating hormones in rats with fructose-induced metabolic changes

Objectives : The aim of this research is to examine the effects fructose-drinking on plasma levels appetite-regulating hormones insulin, leptin and ghrelin in male female rats. Methods Mature Wistar rats were divided as follows: two control groups - (CM) (CF); (FDM) (FDF), received 15% fructose solution. experiment lasted 11 weeks. At end, well lipid glucose profile assessed. Results Plasma concentrations examined elevated groups. However, FDM group only significantly increased compared control. In FDF group, all three showed highest comparison other Conclusion Sex may affect appetite-regulation signals could be a factor contributing degree metabolic changes caused by long-term overconsumption.